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    NCBI Bookshelf. Sunderland MA : Sinauer Associates; Much like control of the bladder, sexual responses are mediated by the coordinated activity of sympathetic, parasympathetic, and somatic innervation. Although these reflexes differ in detail in males and females, basic similarities allow the two sexes to be considered together, not only in humans but in mammals generally see Chapter The relevant autonomic effects include: 1 the mediation of vascular dilation, which causes penile or clitoral erection; 2 stimulation of prostatic or vaginal secretions; 3 smooth muscle contraction of the vas deferens during ejaculation or rhythmic vaginal contractions during orgasm in females; and 4 contractions of the somatic pelvic muscles that accompany orgasm in both sexes. The sacral parasympathetic pathway controlling the sexual organs in both males and females originates in the sacral segments S2—S4 and reaches the target organs via the pelvic nerves.
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    Neural Control and Physiology of Sexual Function: Effect of Spinal Cord Injury

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    Autonomic Regulation of Sexual Function - Neuroscience - NCBI Bookshelf

    Try out PMC Labs and tell us what you think. Learn More. Objective: To present the current understanding of normal anatomy, physiology, sexual physiology, pathophysiology and the consequential sexual changes and dysfunctions following a spinal cord injury SCI. Methods: Narrative review of the latest literature. Results: Peripheral innervations of the pelvis involve 3 sets of efferent neurons coordinated though the pelvic plexus somatic, thoracolumbar sympathetic, and sacral parasympathetic , and these are under cerebral descending excitatory and inhibitory control.
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    The management of erectile dysfunction ED has changed dramatically in recent years, as advances in molecular biology have given us a better understanding of the erectile process as well as the pathophysiology of erectile disorders. Until relatively recently, however, most research in ED focused on peripheral neurophysiology and on the local tissues of the penis, leading to the development of highly effective treatments such as penile injections and sildenafil. There has, however, been growing interest in the role of the central nervous system CNS in the control of erectile function, and researchers have begun to develop medications that target these central mechanisms.
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